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| US Open | ||
| Surface: Hard | Date: Aug. 28 - Sep. 9 | Seed: 10 |
| Round | Opponent | W / L | Result |
| First Round | Storm Hunter | Win | 6-4, 6-0 |
| Second Round | Magdalena Frech | Win | 6-3, 6-3 |
| Third Round | Taylor Townsend | Win | 7-6 (7-0), 6-3 |
| Fourth Round | Xinyu Wang | Win | 6-3, 5-7, 6-1 |
| Quarterfinals | Sorana Cirstea | Win | 6-0, 6-3 |
| Semifinals | Coco Gauff | Loss | 4-6, 5-7 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 14 - Aug. 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Beatriz Haddad Maia | Win | 6-7 (3-7), 6-1, 6-4 |
| Second Round | Petra Martic | Win | 6-3, 3-6, 6-3 |
| Third Round | Maria Sakkari | Win | 6-3, 2-6, 6-3 |
| Quarterfinals | Marie Bouzkova | Win | 3-0 Retired |
| Semifinals | Aryna Sabalenka | Win | 6-7 (4-7), 6-3, 6-2 |
| Final | Coco Gauff | Loss | 3-6, 4-6 |
| Omnium National Bank presented by Rogers | ||
| Surface: Hard | Date: Aug. 7 - Aug. 13 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Anastasia Potapova | Win | 7-6 (7-4), 6-2 |
| Second Round | Sorana Cirstea | Win | 7-5, 6-4 |
| Third Round | Iga Swiatek | Loss | 1-6, 6-4, 4-6 |
| BNP Paribas Poland Open | ||
| Surface: Clay | Date: Jul. 24 - Jul. 30 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Aliaksandra Sasnovich | Win | 4-6, 7-6 (7-0), 6-3 |
| Second Round | Rebecca Sramkova | Loss | 5-7, 6-3, 5-7 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 3 - Jul. 15 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Jule Niemeier | Loss |
| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 10 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Maria Sakkari | Win | |
| Second Round | Nadia Podoroska | Win | |
| Third Round | Irina-Camelia Begu | Win | |
| Fourth Round | Elina Avanesyan | Win | |
| Quarterfinals | Anastasia Pavlyuchenkova | Win | |
| Semifinals | Aryna Sabalenka | Win | |
| Final | Iga Swiatek | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 9 - May 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kamilla Rakhimova | Win | |
| Second Round | Martina Trevisan | Win | |
| Third Round | Camila Giorgi | Win | |
| Fourth Round | Paula Badosa | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 25 - May 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Anett Kontaveit | Win | |
| Second Round | Irina-Camelia Begu | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 21 - Apr. 1 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jil Teichmann | Win | |
| Second Round | Lin Zhu | Win | |
| Third Round | Sorana Cirstea | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Yulia Putintseva | Win | |
| Second Round | Victoria Azarenka | Win | |
| Third Round | Martina Trevisan | Win | |
| Fourth Round | Marketa Vondrousova | Win | |
| Quarterfinals | Elena Rybakina | Loss |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 19 - Feb. 25 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Bernarda Pera | Win | |
| Second Round | Sorana Cirstea | Win | |
| Third Round | Belinda Bencic | Win | |
| Quarterfinals | Jessica Pegula | Loss |
| Qatar Total Energies Open | ||
| Surface: Hard | Date: Feb. 13 - Feb. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Martina Trevisan | Win | |
| Second Round | Caroline Garcia | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Lesia Tsurenko | Win | |
| Second Round | Danielle Collins | Loss |
| ASB Classic | ||
| Surface: Hard | Date: Jan. 1 - Jan. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Xiyu Wang | Win | |
| Second Round | Elena-Gabriela Ruse | Win | |
| Quarterfinals | Rebeka Masarova | Loss |
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