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| WTA Finals Fort Worth | ||
| Surface: Hard | Date: Oct. 31 - Nov. 7 | Seed: 3 |
| Round | Opponent | W / L | Result |
| Round Robin | Maria Sakkari | Loss | 6-7 (6-8), 6-7 (4-7) 6-1, 3-6, 3-6 3-6, 5-7 |
| Round Robin | Ons Jabeur | Loss | 6-7 (6-8), 6-7 (4-7) 6-1, 3-6, 3-6 3-6, 5-7 |
| Round Robin | Aryna Sabalenka | Loss | 6-7 (6-8), 6-7 (4-7) 6-1, 3-6, 3-6 3-6, 5-7 |
| Guadalajara Open Akron | ||
| Surface: Hard | Date: Oct. 17 - Oct. 23 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Elena Rybakina | Win | 2-6, 6-3, 7-6 (10-8) |
| Third Round | Bianca Andreescu | Win | 6-4, 6-4 |
| Quarterfinals | Sloane Stephens | Win | 6-2, 6-2 |
| Semifinals | Victoria Azarenka | Win | 7-6 (7-3), 6-1 |
| Final | Maria Sakkari | Win | 6-2, 6-3 |
| San Diego Open | ||
| Surface: Hard | Date: Oct. 10 - Oct. 16 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Coco Vandeweghe | Win | 6-3, 6-1 |
| Quarterfinals | Madison Keys | Win | 6-4, 7-5 |
| Semifinals | Iga Swiatek | Loss | 6-4, 2-6, 2-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 29 - Sep. 11 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Viktorija Golubic | Win | 6-2, 6-2 |
| Second Round | Aliaksandra Sasnovich | Win | 6-4, 6-4 |
| Third Round | Yue Yuan | Win | 6-2, 6-7 (6-8), 6-0 |
| Fourth Round | Petra Kvitova | Win | 6-3, 6-2 |
| Quarterfinals | Iga Swiatek | Loss | 3-6, 6-7 (4-7) |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 14 - Aug. 21 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marta Kostyuk | Win | |
| Third Round | Emma Raducanu | Win | |
| Quarterfinals | Caroline Garcia | Loss |
| National Bank Open presented by Rogers | ||
| Surface: Hard | Date: Aug. 8 - Aug. 14 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Asia Muhammad | Win | |
| Third Round | Camila Giorgi | Win | |
| Quarterfinals | Yulia Putintseva | Win | |
| Semifinals | Simona Halep | Loss |
| Citi Open | ||
| Surface: Hard | Date: Aug. 1 - Aug. 7 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Hailey Baptiste | Win | |
| Second Round | Daria Saville | Loss |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 27 - Jul. 10 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Donna Vekic | Win | |
| Second Round | Harriet Dart | Win | |
| Third Round | Petra Martic | Loss |
| Roland Garros | ||
| Surface: Red Clay | Date: May 22 - Jun. 5 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Qiang Wang | Win | |
| Second Round | Anhelina Kalinina | Win | |
| Third Round | Tamara Zidansek | Win | |
| Fourth Round | Irina-Camelia Begu | Win | |
| Quarterfinals | Iga Swiatek | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 8 - May 15 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Liudmila Samsonova | Win | |
| Second Round | Anhelina Kalinina | Win | |
| Third Round | Aryna Sabalenka | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 28 - May 8 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Camila Giorgi | Win | |
| Second Round | Kaia Kanepi | Win | |
| Third Round | Bianca Andreescu | Win | |
| Quarterfinals | Sara Sorribes Tormo | Win | |
| Semifinals | Jil Teichmann | Win | |
| Final | Ons Jabeur | Loss |
| Credit One Charleston Open | ||
| Surface: Green Clay | Date: Apr. 4 - Apr. 10 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jasmine Paolini | Win | |
| Third Round | Coco Vandeweghe | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 3 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Sloane Stephens | Win | |
| Third Round | Elena Rybakina | Win | |
| Fourth Round | Anhelina Kalinina | Win | |
| Quarterfinals | Paula Badosa | Win | |
| Semifinals | Iga Swiatek | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 9 - Mar. 20 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marie Bouzkova | Loss |
| Qatar TotalEnergies Open | ||
| Surface: Hard | Date: Feb. 20 - Feb. 26 | Seed: 9 |
| Round | Opponent | W / L | Result |
| First Round | Katerina Siniakova | Win | |
| Second Round | Kaja Juvan | Win | |
| Third Round | Maria Sakkari | Loss |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Feb. 14 - Feb. 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Cori Gauff | Win | |
| Second Round | Ons Jabeur | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 17 - Jan. 30 | Seed: 21 |
| Round | Opponent | W / L | Result |
| First Round | Anhelina Kalinina | Win | |
| Second Round | Bernarda Pera | Win | |
| Third Round | Nuria Parrizas-Diaz | Win | |
| Fourth Round | Maria Sakkari | Win | |
| Quarterfinals | Ashleigh Barty | Loss |
| Sydney Tennis Classic | ||
| Surface: Hard | Date: Jan. 10 - Jan. 15 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Caroline Garcia | Loss |
| Melbourne Summer Set 2 | ||
| Surface: Hard | Date: Jan. 4 - Jan. 9 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Irina-Camelia Begu | Loss |
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