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| bett1open | ||
| Surface: Grass | Date: Jun. 14 - Jun. 20 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Hailey Baptiste |
| Roland Garros | ||
| Surface: Red Clay | Date: May 30 - Jun. 13 | Seed: 28 |
| Round | Opponent | W / L | Result |
| First Round | Lin Zhu | Win | 6-4, 4-6, 6-4 |
| Second Round | Tereza Martincova | Win | 6-3, 6-3 |
| Third Round | Sofia Kenin | Loss | 6-4, 1-6, 4-6 |
| Internationaux de Strasbourg | ||
| Surface: Clay | Date: May 23 - May 29 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Arantxa Rus | Loss | 4-6, 4-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 9 - May 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Daria Kasatkina | Win | 7-5, 6-3 |
| Second Round | Naomi Osaka | Win | 7-6 (7-2), 6-2 |
| Third Round | Ekaterina Alexandrova | Win | 6-2, 6-4 |
| Quarterfinals | Petra Martic | Loss | 5-7, 4-6 |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 29 - May 9 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Sorana Cirstea | Win | 7-6 (7-5), 6-3 |
| Second Round | Victoria Azarenka | Win | Retired |
| Third Round | Aryna Sabalenka | Loss | 1-6, 2-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 23 - Apr. 4 | Seed: 29 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Storm Sanders | Win | 6-3, 6-4 |
| Third Round | Karolina Pliskova | Win | 6-1, 4-6, 6-4 |
| Fourth Round | Maria Sakkari | Loss | 4-6, 6-2, 6-7 (6-8) |
| Dubai Duty Free Tennis Championships | ||
| Surface: Hard | Date: Mar. 7 - Mar. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Yaroslava Shvedova | Win | 6-2, 6-1 |
| Second Round | Kristina Mladenovic | Win | 6-1, 6-2 |
| Third Round | Karolina Pliskova | Win | 6-0, 6-2 |
| Quarterfinals | Elise Mertens | Loss | 7-5, 5-7, 0-6 |
| Qatar Total Open 2021 | ||
| Surface: Hard | Date: Mar. 1 - Mar. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Qiang Wang | Win | 6-3, 6-1 |
| Second Round | Jelena Ostapenko | Win | 6-2, 7-5 |
| Quarterfinals | Karolina Pliskova | Win | 6-3, 6-1 |
| Semifinals | Petra Kvitova | Loss | 4-6, 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Feb. 8 - Feb. 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Victoria Azarenka | Win | 7-5, 6-4 |
| Second Round | Samantha Stosur | Win | 6-0, 6-1 |
| Third Round | Kristina Mladenovic | Win | 6-2, 6-1 |
| Fourth Round | Elina Svitolina | Win | 6-4, 3-6, 6-3 |
| Quarterfinals | Jennifer Brady | Loss | 6-4, 2-6, 1-6 |
| Yarra Valley Classic | ||
| Surface: Hard | Date: Jan. 31 - Feb. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Kristina Mladenovic | Win | 6-4, 6-1 |
| Second Round | Mona Barthel | Win | 6-4, 7-5 |
| Third Round | Sofia Kenin | Loss | 7-5, 5-7, 2-6 |
| Abu Dhabi WTA Women's Tennis Open | ||
| Surface: Hard | Date: Jan. 6 - Jan. 13 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Elina Svitolina | Loss | 4-6, 3-6 |
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