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| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 11 | Seed: 23 |
| Round | Opponent | W / L | Result |
| First Round | Jaume Munar | Win | 6-1, 2-6, 7-6 (7-5), 6-1 |
| Second Round | Yannick Hanfmann |
| Open Parc Auvergne-Rhone-Alpes Lyon | ||
| Surface: Clay | Date: May 21 - May 27 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Juan Pablo Varillas | Win | 6-2 Retired |
| Quarterfinals | Jack Draper | Win | 4-6, 6-4, 6-3 |
| Semifinals | Cameron Norrie | Win | 6-3, 6-0 |
| Final | Arthur Fils | Loss | 3-6, 5-7 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 10 - May 21 | Seed: 24 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Yibing Wu | Win | 4-6, 6-2, 6-3 |
| Third Round | Gregoire Barrere | Win | 6-7 (0-7), 6-2, 6-2 |
| Fourth Round | Jannik Sinner | Win | 6-7 (3-7), 6-2, 6-2 |
| Quarterfinals | Casper Ruud | Loss | 6-7 (5-7), 4-6 |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 26 - May 7 | Seed: 24 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Pedro Cachin | Loss | 1-6, 6-7 (6-8) |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 17 - Apr. 23 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Francesco Passaro | Win | 6-2, 6-2 |
| Third Round | Casper Ruud | Win | 7-6 (7-5), 6-3 |
| Quarterfinals | Daniel Evans | Loss | 6-2, 5-7, 3-6 |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 9 - Apr. 16 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Cameron Norrie | Win | 6-3, 6-4 |
| Second Round | Matteo Berrettini | Loss | 7-5, 6-7 (1-7), 4-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 2 | Seed: 25 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Aleksandar Kovacevic | Win | 6-4, 6-4 |
| Third Round | Felix Auger-Aliassime | Win | 6-2, 7-5 |
| Fourth Round | Lorenzo Sonego | Win | 3-6, 6-3, 6-2 |
| Quarterfinals | Karen Khachanov | Loss | 3-6, 2-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: 27 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jack Sock | Win | 4-6, 6-3, 6-4 |
| Third Round | Felix Auger-Aliassime | Loss | 5-7, 4-6 |
| Chile Dove Men+Care Open | ||
| Surface: Clay | Date: Feb. 27 - Mar. 5 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Tomas Martin Etcheverry | Loss | 3-6, 6-3, 3-6 |
| Rio Open presented by Claro | ||
| Surface: Clay | Date: Feb. 20 - Feb. 26 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Roberto Carballes Baena | Win | 4-6, 6-3, 6-3 |
| Second Round | Bernabe Zapata Miralles | Loss | 1-6, 6-4, 1-6 |
| Argentina Open | ||
| Surface: Clay | Date: Feb. 13 - Feb. 19 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Yannick Hanfmann | Win | 6-2, 4-6, 7-5 |
| Second Round | Jaume Munar | Win | 6-2, 6-1 |
| Quarterfinals | Bernabe Zapata Miralles | Loss | 3-6, 7-6 (7-4), 3-6 |
| Cordoba Open | ||
| Surface: Clay | Date: Feb. 6 - Feb. 12 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Federico Delbonis | Win | |
| Quarterfinals | Federico Coria | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 29 | Seed: 28 |
| Round | Opponent | W / L | Result |
| First Round | Guido Pella | Win | |
| Second Round | Corentin Moutet | Win | |
| Third Round | Felix Auger-Aliassime | Loss |
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